Luke and Jo, our intrepid Marathon runners have hit their stride in our second selection of videos. They’re swimming, fundraising, running to and from work and even getting very muddy on assault courses. Find out more about the ways that they’re tackling training for the impending Marathon, now just weeks away!

Mothering Sunday is approaching fast – less than two weeks to go now! So if you’re searching for a present with a little more meaning, have a look at our selection of gifts, specially for marvellous mums. 100% of profits help support the young patients at Great Ormond Street Hospital. Buy your gifts soon to ensure you have something ready for the 18th of March!

Our son Robbie was diagnosed with Eosinophilic Gastrointestinal Disorder (EGID) three years ago and has been under the care of Dr Shah and Dr Thapar at Great Ormond Street Hospital since then. Having seen first-hand the extraordinary commitment and dedication of the Gastro team we jumped at the opportunity to help out with fundraising for their much needed research.

Channel 4′s Comedy Gala – the biggest live stand-up event in the country – returns to the O2 Arena for the third year this May. Over 20 top comedy acts will entertain the audience on Friday 11 May 2012 in aid of a new operating theatre at Great Ormond Street Hospital.

Many runners will be choosing 2012 to take on their first big running challenge. Several of you will be tackling your first ever marathon – and that’s a very daunting prospect, we know. Two staff members at Great Ormond Street Hospital Children’s Charity have decided to share the pain, anguish and – eventually – joy of the experience of preparing for a marathon with a series of video blogs. Here is their story so far.

Kiss it Better is an initiative to raise money for research into the causes and treatment of childhood cancer – the biggest disease affecting children today. The appeal was co-founded by Clinique and Carmel Allen, whose daughter, Josephine, was treated at the hospital for neuroblastoma. To raise money for the campaign, Clinique has created a special new limited edition Kissable Lip Set.

Help us celebrate Great Ormond Street Hospital’s 160th birthday this February and get baking like crazy to help children with cancer for our Bake it Better appeal. Cake sales are an easy and delicious way to raise money. It’s easy peasy, lemon squeezy to take part!

My daughter Maisey had been having some specialist treatment for some complex digestive issues, and last February I was scrolling through the Great Ormond Street Hospital website to find some information, but I came away signing up for the Inca Trail Trek 2011.

In September this year myself and 40 of my friends will be taking the plunge and jumping out of a plane for Great Ormond Street Hospital Children’s Charity. I’ve got so many mixed emotions about it! I’m really, really looking forward to it but on the other hand jumping 10’000ft – yikes!